Page 6 - SRPSKO DRUŠTVO ISTRAŽIVAČA RAKA

What is new in care of Adolescents and Young Adults, AYA with cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49
Control of IFN-γ Responsiveness and Metasta c Poten al in Melanoma by GSTA4 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50

MicroRNAs – biomarker proper es in prostate cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52

Signifi cance of molecular diagnos cs in therapy of chronic lymphocy c leukemia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54

ORAL PRESENTATIONS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57

The PDK-1 inhibitor GSK2334470 induces cell death and G1 cell cycle arrest in human pancrea c cancer cells . . . . . . 57
Suppressor Eff ects ofTheMixed LigandPla num (II) Saccharinate Complexes(trans-[Pt(sac) (PPh ) ] and trans-[Pt(sac)
2
3 2
2
(PPh Cy) ])on In Vitro And In Vivo Angiogenesis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57
2 2
All-trans re noic acid ac vi es in Merkel cell carcinoma: implica on of the re noic gene signature . . . . . . . . . . . . . . 58
Predic ng response to chemoradiotherapy in locally advanced rectal cancer using MRI-based radiomics features . . . 59

Transcriptomic profi ling of the early stage squamous cell lung cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59
The role of p53 family in melanoma development and therapy resistance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 60

The an cancer eff ects of triterpene saponin deglucocyclamine isolated from Cyclamen hederifolium. . . . . . . . . . . . . .61

The eff ect of diiron thiocarbyne complex on tumor cells of diff erent grade. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61

The eff ects of cispla n-ibuprofen conjugate free and immobilized in mesoporous nanostructured silica on the change of
morphology of mouse melanoma cells, and an tumor poten al in vivo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .62
Role of Claudins 3, 4 and 7 in Triple Nega ve Breast Cancer progression. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63

Impairment of cysta n F ac va on can increase the cytotoxicity of NK cells. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63

Cispla n-Killed Cells as a Preferable Method for Genera ng Tumor Cell-Based Vaccines. . . . . . . . . . . . . . . . . . . . . . . . . 64

Modes of Ac vity and Prognos c Signifi cance of the Hedgehog-GLI Signaling Pathway in Prostate Cancer. . . . . . . . . . 64

Platelet-released factors boost prolifera on of mul ple myeloma cells and changes in bone marrow stroma with
implica ons of NFκB pathway involvement . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65

In vitro an cancer ac vity of kaempferol-derived fl avonoids against pancrea c adenocarcinoma . . . . . . . . . . . . . . . . . 66

Amassing a treasure trove for drug repurposing using chemoproteomics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66

Characteriza on of heterogeneity of cancer-associated fi broblasts isolated from PDAC pa ents . . . . . . . . . . . . . . . . . . 67
Exploring the an cancer ac vity of essen al oil of Satureja montana L. from Montenegro . . . . . . . . . . . . . . . . . . . . . . 67

POSTER PRESENTATIONS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69

A pilot study of the associa on between variants rs25487 of XRCC1 gene, rs1801320 of RAD51 gene, and rs13181 of
ERCC2 gene and acute toxicity of rаdia on therapy a er radical prostatectomy in pa ents with prostate cancer . . . . 69
Overview and data management of gastropancrea c oncology biobank sample and data collec on. . . . . . . . . . . . . . . 69

Detec on of resistant EGFR T790M muta on from liquid biopsy samples of pa ents with advanced non-small cell lung
cancer: comparison of qPCR and dPCR detec on methods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71

Histomics: Bridging Radiomics and Histopathology Towards Advancing Prognos ca on of Breast Cancer Metastasis . 71
Eff ects of promoter methyla on and muta on on BRCA1/2 expression in ovarian cancer. . . . . . . . . . . . . . . . . . . . . . . . 74

Ultra-short cfDNA fragment detec on during systemic therapy of advanced-stage colorectal cancer . . . . . . . . . . . . . . 75